Nitric oxide, exercise recovery, mitochondrial energy, antioxidant defense
Super Human Blend (SHB)
A nine-component amino acid and cofactor blend studied for nitric-oxide production, mitochondrial energy, exercise recovery, antioxidant defense, collagen support, and metabolic resilience.
Administration Reference
Intramuscular
Source / Evidence Context
Commonly reported use — not established guidance
Formulation & Context
A ready-to-use injectable amino acid and metabolic-cofactor blend containing L-arginine, L-ornithine, L-citrulline, L-lysine, L-glutamine, L-proline, taurine, L-carnitine, and N-acetylcysteine (NAC).
Dose Information
0.5–1.0 mL
Frequency
3–4 times weekly
Duration / Cycle
4–8 weeks in performance and recovery protocols
Off-Cycle
Often used intermittently; no defined off-cycle
Timing
Pre-exercise for endurance goals, Post-exercise for recovery and amino-acid replenishment.
Storage Guidance
A cool, dry place away from direct light and moisture
Supplies
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Listings are not a required kit or confirmation of suitability for a particular peptide, formulation, or route. Check the product specifications and intended use.
Syringes & transfer supplies
BH Supplies Insulin Syringes U-100 29G 1ml/cc 1/2″ (12.7mm) Pack of 100 Pcs29g 1/2" syringePolybag, 100 Unit Capacity, 1/2” Needle Length, Bold Markings for Accurate Dosing, Disposable, Box of 100View at AMAZON →
Protective supplies & disposal
MED PRIDE Sterile Alcohol Prep Pads1 BOX OF 200INDIVIDUALLY WRAPPED ISOPROPYL ALCOHOL WIPES, PACK OF 1 BOX OF 200, MEDIUM SIZE PREP PADSView at AMAZON →
Inspire Black Nitrile Gloves HEAVY DUTY 6 Mil100ctView at AMAZON →
Square Sharps Container, 2 QuartQTY 1View at AMAZON →
Commonly Reported Uses
Exercise recovery; endurance; nitric-oxide and blood-flow support; post-training soreness; mitochondrial energy production; fat oxidation; glutathione support; antioxidant defense; collagen and connective-tissue support; ammonia clearance; hydration and cellular resilience.
Commonly Reported Indicators
Improved exercise pump, increased training endurance, reduced post-exercise fatigue, improved recovery between sessions, reduced soreness, more consistent energy, and improved perceived exercise capacity are commonly reported.
Mechanism Overview
Arginine and citrulline support nitric-oxide production, while ornithine participates in urea-cycle ammonia clearance. Carnitine transports long-chain fatty acids into mitochondria for beta-oxidation. NAC supports glutathione synthesis, taurine contributes to cell-volume and membrane regulation, and lysine/proline provide substrates important to collagen and connective-tissue biology.
Safety
Safety Considerations
Safety depends heavily on concentration, injection volume, formulation quality, and individual tolerance. Arginine and citrulline may promote vasodilation and lower blood pressure, while concentrated amino-acid preparations may cause local discomfort. NAC can produce nausea, flushing, sulfur-like odor, or hypersensitivity reactions in some settings. Carnitine and amino-acid loads may also produce gastrointestinal or metabolic effects.
Reported Adverse Effects
Injection-site pain, burning, redness or swelling; nausea; headache; flushing; dizziness; transient blood-pressure reduction; gastrointestinal discomfort; sulfur-like odor associated with NAC; and soreness following IM administration.
Contraindications & Cautions
Additional caution is appropriate with low blood pressure, concurrent vasodilator or antihypertensive therapy, significant kidney or liver disease, disorders of amino-acid metabolism, pregnancy or breastfeeding, and known hypersensitivity to any component.
Cancer Considerations
Editorial evidence assessment, not a validated risk score or clearance for use. Unknown risk does not mean low risk; these notes do not establish safety during active cancer or remission.
Cancer Concern Assessment
Low theoretical concern
Basis for Concern
The blend does not primarily stimulate GH/IGF-1, VEGF, or telomerase. However, arginine metabolism, glutamine availability, redox signaling, and NAC-related glutathione pathways are all relevant to tumor-cell metabolism. These mechanisms are highly context dependent and do not establish that the blend promotes malignancy.
Active Cancer
Caution due to mechanism
NAC and several amino acids influence redox balance and cellular metabolism, which may interact with certain chemotherapy or radiation strategies. Use during active cancer treatment should therefore be considered in the context of the specific malignancy and treatment regimen rather than assuming either benefit or harm.
Prior Cancer / Remission
Individualized caution
No evidence suggests that this amino-acid blend carries the same theoretical concern as GH-axis or strongly angiogenic compounds. No specific remission interval is established.
Status
Regulatory Status
Super Human Blend is not an FDA-approved combination drug. It is a proprietary formulation name used for injectable amino-acid and metabolic-cofactor blends. Individual ingredients such as NAC and L-carnitine have established medical uses, but the combined formulation does not have an FDA-approved performance or recovery indication.
Development / Research Status
Research status unclear
Market Classification
Research-use compound
Status Notes
“Super Human Blend” is a formulation name rather than a unique molecular compound. Current versions commonly contain nine components totaling approximately 865 mg/mL, but composition should always be verified from the specific product label or COA because formulations can differ.
Research & Evidence
Evidence Level
Insufficient evidence
Research Last Reviewed
2026-09-06
Research Overview
The proprietary combination itself has not been studied as a standardized clinical product, but its individual components have substantial human and mechanistic research involving nitric-oxide production, exercise performance, muscle recovery, mitochondrial fatty-acid transport, antioxidant defense, collagen metabolism, and amino-acid physiology.
Human Research
L-citrulline and L-arginine have been studied extensively for nitric-oxide availability and exercise outcomes, although results vary depending on dose, population, and endpoint. Citrulline has shown potential effects on exercise performance through increased arginine availability and nitric-oxide synthesis.
L-carnitine has human evidence involving exercise recovery and muscle damage. A systematic review and meta-analysis found reductions in muscle soreness and selected markers of exercise-induced muscle damage, including creatine kinase, myoglobin, and LDH.
Taurine has been investigated for aerobic and resistance-exercise performance, fatigue, antioxidant activity, and lactate responses. Human studies suggest dose- and exercise-dependent effects rather than a uniform performance benefit.
Glutamine has been studied extensively in athletes and recovery settings. A meta-analysis of 47 studies found limited effects on most performance endpoints, although specific metabolic and immune-related outcomes varied by dose and formulation.
Animal Research
Animal research supports the established physiological roles of carnitine in fatty-acid transport, taurine in membrane and cellular homeostasis, NAC in glutathione metabolism, and arginine/citrulline/ornithine in nitric-oxide and urea-cycle pathways. These studies support the biological rationale for combining the ingredients but do not establish superiority of the proprietary blend.
In Vitro Research
NAC acts largely by increasing intracellular cysteine availability and supporting glutathione synthesis. Proline is a major structural component of collagen, while lysine is required for collagen cross-linking and structural integrity. Arginine serves as a nitric-oxide synthase substrate, and carnitine is required for mitochondrial transport of long-chain fatty acids.
References
Super Human Blend Certificate of Analysis. Nine-component sterile amino-acid/metabolic-cofactor formulation: L-arginine, L-ornithine, L-citrulline, L-lysine, L-glutamine, L-proline, taurine, L-carnitine, and NAC. 2026.
Super Human Blend — 9-component amino acid recovery and performance formulation, 865 mg/mL. 2026.
Super Human Blend Composition Reference — L-Arginine 110 mg, L-Ornithine 110 mg, L-Citrulline 120 mg, L-Lysine 70 mg, L-Glutamine 40 mg, L-Proline 60 mg, Taurine 60 mg, L-Carnitine 220 mg, NAC 75 mg.
Harnden CS, Agu J, Gascoyne T. Effects of citrulline on endurance performance in young healthy adults: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2023;20(1):2209056. PMID 37155582. DOI 10.1080/15502783.2023.2209056.
Porto AA, Gonzaga LA, Benjamim CJR, Valenti VE. Absence of Effects of L-Arginine and L-Citrulline on Inflammatory Biomarkers and Oxidative Stress in Response to Physical Exercise: A Systematic Review with Meta-Analysis. Nutrients. 2023;15(8):1995. PMID 37111214. DOI 10.3390/nu15081995.
Yarizadh H, Shab-Bidar S, Zamani B, et al. The Effect of L-Carnitine Supplementation on Exercise-Induced Muscle Damage: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Am Coll Nutr. 2020;39(5):457-468. PMID 32154768. DOI 10.1080/07315724.2019.1661804.
Chen Q, Li Z, Pinho RA, et al. The Dose Response of Taurine on Aerobic and Strength Exercises: A Systematic Review. Front Physiol. 2021;12:700352. PMID 34497536. DOI 10.3389/fphys.2021.700352.
Ahmadi AR, Rayyani E, Bahreini M, et al. The effect of glutamine supplementation on athletic performance, body composition, and immune function: a systematic review and meta-analysis of clinical trials. Clin Nutr. 2019. PMID 29784526. DOI 10.1016/j.clnu.2018.05.001.
Albaugh VL, Mukherjee K, Barbul A. Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. J Nutr. 2017;147(11):2011-2017. PMID 28978679. DOI 10.3945/jn.117.256404.
Samuni Y, Goldstein S, Dean OM, Berk M. The chemistry and biological activities of N-acetylcysteine. Related NAC/glutathione literature establishes NAC primarily as a cysteine donor supporting intracellular glutathione synthesis.